PepGuide — The World's Most Comprehensive Peptide Research Encyclopedia
The independent, open-access peptide encyclopedia. 365 peptides documented with 1,600+ peer-reviewed citations. Every claim linked to PubMed. No commercial bias.
PepGuide — Peptide Research Encyclopedia
The independent, research-focused encyclopedia of peptides. Every article is built on published scientific literature with direct links to primary sources. No commercial bias. No paywalls. Updated weekly.
365 peptides documented · 1,600+ peer-reviewed citations · Updated weekly · Peer-reviewed sources only · No commercial bias
Why PepGuide?
- Independent. No vendor relationships, no affiliate links, no sponsored content. Every editorial decision is driven by the science.
- Cited. Every factual claim links to its source on PubMed. Readers can verify anything in one click.
- Updated weekly. New research is reviewed and integrated every week. Each page shows its last update date.
- Research-first. We distinguish between in vitro, animal, and human data. We report limitations. We note when evidence is preliminary.
Read more about our editorial standards and methodology.
Browse by Category
🔥 GLP-1 & Metabolic (68)
Semaglutide, Tirzepatide, Retatrutide, AOD-9604, 5-Amino-1MQ — GLP-1 agonists and metabolic regulators.
📈 Growth Hormone (22)
Sermorelin, CJC-1295, Ipamorelin, GHRP-2/6, MK-677 — GHRH analogs and secretagogues.
🩹 Healing & Repair (35)
BPC-157, TB-500, GHK-Cu, KPV — angiogenesis, cell migration, and tissue regeneration.
⏳ Longevity & Anti-Aging (22)
Epithalon, MOTS-c, Humanin, SS-31 — telomerase, mitochondria, and geroprotection.
🧠 Cognitive & Nootropic (48)
Semax, Selank, Dihexa, Cerebrolysin, Cortagen — nootropic and neuroprotective peptides.
⚡ Sexual Health & Hormones (27)
PT-141, Kisspeptin-10, Gonadorelin, Oxytocin — melanocortin agonists and reproductive health.
✨ Skin & Cosmetic (38)
GHK-Cu, Argireline, SNAP-8, Matrixyl — signal peptides, copper peptides, and collagen stimulators.
🔬 Russian Bioregulators (18)
The complete Khavinson family — organ-specific short peptides for gene expression modulation.
🛡️ Antimicrobial & Immune (21)
LL-37, Thymosin Alpha-1, KPV, Defensins — host defense peptides and immunomodulators.
💊 Pain & Inflammation (9)
BPC-157, DSIP, ARA-290, VIP — analgesic and anti-inflammatory peptides.
❤️ Cardiovascular (10)
Cardiogen, ANP, BNP, Apelin — cardiac repair and vascular health research.
💪 Muscle & Performance (4)
Ostarine, LGD-4033, YK-11 — SARMs and muscle-performance research compounds.
🦴 Bone & Joint (4)
Abaloparatide, ACE-031, PTH analogs — bone density and joint research.
🔎 Cancer Research (10)
Angiostatin, Endostatin, EP100 — anti-angiogenic and tumor-targeting peptides.
🧪 Other Research Peptides (29)
Specialized research peptides, novel compounds, and emerging areas of study.
Latest Research
March 2026 Updates
365 peptide profiles, 8 research guides, 16 categories, and regulatory news.
Research Alerts
Active clinical trials: SELECT, SURMOUNT, TRIUMPH, REDEFINE, EMANATE, and more.
Changelog
Complete log of every change to the wiki.
Most Popular Peptides
| Peptide | Category | Why It's Notable |
|---|---|---|
| BPC-157 | Healing & Repair | 100+ preclinical studies; broadest tissue-repair evidence base of any research peptide |
| TB-500 | Healing & Repair | Cardiac progenitor cell activation; fundamental role in cell migration |
| Semaglutide | Metabolic | FDA-approved GLP-1 agonist; SELECT trial cardiovascular outcomes data |
| GHK-Cu | Longevity / Skin | Modulates 4,000+ genes; the most broadly active tripeptide known |
| Epithalon | Longevity | Telomerase activation; Khavinson's flagship longevity peptide |
| Ipamorelin | Growth Hormone | Cleanest GH secretagogue profile; selective ghrelin mimetic |
| Semax | Cognitive | BDNF upregulation; Russia's most-prescribed nootropic peptide |
| Thymosin Alpha-1 | Immune | 28-amino acid thymic peptide; approved in 35+ countries |
| PT-141 | Sexual Health | FDA-approved (Vyleesi); melanocortin-based sexual function |
| Tirzepatide | Metabolic | Dual GIP/GLP-1 agonist; 22.5% weight loss in SURMOUNT-1 |
Essential Research Guides
| Guide | Description |
|---|---|
| BPC-157 Complete Guide | All forms, routes, doses, and research |
| TB-500 Complete Guide | Thymosin beta-4 research consolidated |
| GLP-1 Agonist Comparison | Head-to-head efficacy and side effect data |
| Peptide Stacking Guide | Research-based combinations for every goal |
| Peptide Storage & Reconstitution | BAC water, temps, freeze-thaw, stability |
| Peptide Administration Guide | SC, IM, intranasal, sublingual, oral techniques |
| How to Read Peptide Research | Interpret clinical trials, understand peer review, evaluate study quality |
| Peptide Research Databases | PubMed, ClinicalTrials.gov, ChEMBL, PDB, UniProt — how to use each |
Getting Started
Peptides are short chains of amino acids (typically 2-50 residues) that act as signaling molecules in the body. Each profile in this wiki includes:
- Mechanism of action — how the peptide works at the molecular level
- Research summary — key findings from preclinical and clinical studies
- Quick reference table — molecular weight, sequence, CAS number, half-life
- Scientific references — links to published papers on PubMed
- Citation count — number of peer-reviewed sources backing each profile
Browse the full A-Z index with all 365 peptide profiles, or use the search bar above to find any peptide by name.
About PepGuide
PepGuide is an independent educational resource. Read about our mission and editorial standards, our research methodology, or learn how to read peptide research.
Disclaimer
This wiki is an independent educational resource for research purposes only. Content is based on published scientific literature and does not constitute medical advice. Peptides discussed here are research compounds — consult qualified professionals for any health-related decisions. No commercial affiliations influence our content.